Publications

RECENT PUBLICATIONS

Drews, K., Calgi, M.P., Harrison, W.C., Drews, C.M., Costa-Pinheiro, P., Shaw, J.J.P., Jobe, K.A., Nelson, E.A., Han, J.D., Fox, T., et al. (2019). Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis. Journal of Virology 93, e00017–e00019.

Hulseberg, C.E., Fénéant, L., Wijs, K.M.S.-D., Kessler, N.P., Nelson, E.A., Shoemaker, C.J., Schmaljohn, C.S., Polyak, S.J., White, J.M., and Dermody, T.S. (2019). Arbidol and Other Low-Molecular-Weight Drugs That Inhibit Lassa and Ebola Viruses. Journal of Virology 93, e02185–18.

Dyall, J, E.A. Nelson, L.E. DeWald, R. Guha, B. Hart, H. Zhou et al. 2018. Identification of Combinations of Approved Drugs with Synergistic Activity Against Ebola Virus in Cell Cultures. J. Infect. Diseases. DOI: 10.1093/infdis/jiy304

Hulseberg, CE, Feneant, L, Syzmanska, K, and White, JM. 2018. Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments. mBio. 9:e01818-17. PMID 29295909.

Yang S-T, Kreutzberger AJB, Kiessling V, Ganser-Pornillos BK, White JM, Tamm LK. 2017. HIV virions sense plasma membrane heterogeneity for cell entry. Sci Adv 3:e1700338.

Lee, J et. 2017. Structure of the Ebola Virus Envelope Protein MPER/TM Domain and its Interaction with the Fusion Loop Explains their Fusion Activity. PNAS. 114:E7987-E7996.

Nelson EA et al. 2017. The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection. PLoS Negl Trop Dis 11:e0005540.

White, J.M. and G.R. Whittaker. 2016. Fusion of Enveloped Viruses in Endosomes. Traffic. 10.1111/tra.12389.

Tran, E. E. H., Nelson, E. A., Bonagiri, P., Simmons, J. A., Shoemaker, C. J., Schmaljohn, C. S., et al. (2016). Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry. J. Virol. 90:7618-7627.

Nelson EA, Barnes AB, Wiehle RD, Fontenot GK, Hoenen T, White JM. 2016. Clomiphene and Its Isomers Block Ebola Virus Particle Entry and Infection with Similar Potency: Potential Therapeutic Implications. Viruses 8:206.

L.M. Johansen, L.E. DeWald, C.J. Shoemaker, B.G. Hoffstrom, C.M. Lear-Rooney, A. Stossel, E. Nelson, S.E. Delos, J.A. Simmons, J.M. Grenier, L.T. Pierce, H. Pajouhesh, J. Lehár, L.E. Hensley, P.J. Glass, J.M. White, and G.G. Olinger. 2015. A Screen of Approved Drugs and Molecular Probes Identifies Therapeutics with Anti-Ebolavirus Activity. Sci. Transl. Med. 7:290ra89.

R.M. Mingo, J.A. Simmons, C.J. Shoemaker, E.A. Nelson, R.S. D’Souza, J.E. Casanova and J.M. White. 2015. Ebola virus and Severe Acute Respiratory Syndrome Coronavirus Display Late Cell Entry Kinetics: Evidence that Transport to NPC1+ Endolysosomes is a Rate-Defining Step. J. Virol. 89:2931-2943.

J. A. Simmons, R.S. D’Souza, M. Ruas, A. Galione, J.E. Casanova, and J.M. White. 2015. Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes. J. Virol. 90(1), 605–610.

Yang S-T, Kiessling V, Simmons JA, White JM, Tamm LK. 2015. HIV gp41-mediated membrane fusion occurs at edges of cholesterol-rich lipid domains. Nat. Chem. Biol. 11:424–431.

Gregory, S.M., P. Larsson, E.A. Nelson, P.M. Kasson, J.M. White, and L.K. Tamm. 2014. Ebolavirus Entry Requires a Compact Hydrophobic Fist at the Tip of the Fusion Loop. J Virol. 88: 6636-6649.

Tran, E.E.H., J.A. Simmons, A. Bartesaghi, C.J. Shoemaker, E.A. Nelson, J.M. White, and S. Subramaniam. 2014. Spatial localization of the Ebola glycoprotein mucin-like domain using cryo-electron tomography. J Virol.; 88: 10958.

M. Johansen, J. M. Brannan, S. E. Delos, C. J. Shoemaker, A. Stossel, C. Lear, B. G. Hoffstrom, L.E. DeWald, K. L. Schornberg, C. Scully, J. Lehár, L. E. Hensley, J. M. White, G. G. Olinger. 2013. FDA-Approved Selective Estrogen Receptor Modulators Inhibit Ebola Virus Infection. Sci. Transl. Med. 5, 190rar79.

White, J.M. and K. L. Schornberg. 2012. A New Player in the Puzzle of Filovirus Entry. Nat. Rev. Microbiol. 10:317-322.

Brecher,M., K.L. Schornberg, S.E. Delos, M.L. Fusco, E.O. Saphire, and J.M. White. 2012. Cathepsin Cleavage Potentiates the Ebolavirus Glycoprotein to Undergo a Subsequent Fusion Relevant Conformational Change. J. Virol. 86: 364-72.

Cardone G, M. Brecher, J. Fontana, D.C. Winkler, C. Butan, J.M. White, and A.C. Steven. 2012. Visualization of the Two-Step Fusion Process of the Retrovirus Avian Sarcoma/Leukosis Virus by Cryo-Electron Tomography. J. Virol. 86:12129.

Gregory, S.M., E. Harada, B. Liang, S. Delos, J.M. White, and L.K. Tamm. 2011. Structure and function of the complete internal fusion loop from ebolavirus GP2. Proc. Nat’l. Acad. Sci. 108:11211-11216.

Avinoam, O., K. Fridman, C. Valansi, I. Abutbul, T. Zeev-Ben-Mordehai, U.E. Maurer, A. Sapir, D. Danino, K. Grünewald, J.M. White, and B. Podbilewicz. 2011. Conserved Eukaryotic Fusogens can Fuse Viral Envelopes to Cells. Science. 332: 589-592.

 A complete list of Dr. White’s published work can be found at My Bibliography.

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